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Table of Contents
Background and Overview
Reasons for Action
Identifying Chemical Hazards - Labeling Systems
Related Efforts, Tools, and Resources
Case Studies and Examples
Where to Go for Help
Complete List of Links

Alternative technologies / Assessment / Best management practices / Chemical engineering / Chemical industry / Chemical spills / Chemical tracking / Chemical treatment / Chemicals / Chemistry / Cleaning compounds / Coating processes / Coatings / Disinfection and disinfectants / Energy conservation / Environmental chemistry / Environmental degradation / Environmental exposure / Environmental health / Environmental management / Environmental protection / Environmentally safe products / Health / Health effects / Incentives / Lean and environment / Paint / Products / Solvents / Toxic chemicals / Toxic release inventory / Toxicity / Toxicity testing / Toxicology / Wood / Wood waste

Alphabetical Listing of Reference Documents by Title
NOTE: [PDF] links require Acrobat Reader from Adobe.

Alpha Gary Reduces Use of Lead
Abstract: The Lead Reduction Pilot Program evaluated the use of alternatives to lead compounds in their products. They successfully incorporate alternatives into their design process and reduced lead time.
Source: Toxics Reduction Institute

American Apparel & Footwear Association Restricted Substance List (RSL)
Abstract: This RSL provides apparel and footwear companies with information related to regulations and laws that restrict or ban certain chemicals/substances in finished home textile, apparel, and footwear around the world.
Source: American Apparel & Footwear Association

Assessing the Safety of Chemical Alternatives
Abstract: Washington State Department of Ecology is working with 7 other member states of the Interstate Chemicals Clearinghouse (IC2) to create alternatives assessment guidance. Drafts and related documents can be found at this link.
Source: WA State Dept of Ecology (and Others)

Abstract: An organization that promotes safer, more environmentally friendly chemicals for workplaces that would normally use dangerous chemicals.
Source: Clean Production Action

California's Green Chemistry Initiative
Abstract: Reducing impacts of toxic chemicals on public health and the environment by expanding P2, developing green chemistry workforce education and training, creating an online product ingredient network and toxics clearinghouse, requiring industry to find greener and safer alternatives through regulations, and moving toward a "cradle to cradle" economy.
Source: California Department of Toxic Substances Control

ChemHAT - Chemical Hazard and Alternatives Toolbox
Abstract: Tool/database for gleaning hazard information about many chemicals. Provides icons for hazards, exposure and protection information, and links to data and case studies for safer alternatives.
Source: IUE-CWA, the Industrial Division of the Communications Workers of America and the BlueGreen Alliance (BGA)

Chemical Assessment and Ranking System (CARS)
Abstract: A decision support tool that uses a credible database of chemical hazard related information, in conjunction with chemical use, to assess and rank chemicals and set goals for substituting or eliminating.
Source: Zero Waste Alliance

Chemicals Prioritization: An Approach by the American Chemistry Council (ACC)
Abstract: The American Chemistry Council's (ACC)'s approach to prioritizing chemicals is used to identify priority substances that should be further evaluated and could lead to risk management measures. The ACC's approach is both science and risk-based, and utilizes existing data used by industry and regulation.
Source: American Chemistry Council

Abstract: An online database of institutional and industrial (I&I) cleaning product ingredient chemicals, providing verified information about the environmental and human health attributes of listed ingredients
Source: GreenBlue

Column Model for Chemical Substitutes Assessment [PDF]
Abstract: A model to use risk and safety data of a chemical to assess potential toxicity or hazard to humans and the evironment.
Source: BGIA

Environmentally Benign Resins and Additives, for Use in the Wire and Cable Industry
Abstract: Results of a research project on the technical, economic and environmental feasibility of using alternative resins to polyvinyl chloride (PVC) in the wire and cable industry
Source: Toxics Use Reduction Institute

Five Chemicals Study (Executive Summary)
Abstract: Report of research on 5 hazardous chemicals, prioritization of their use, prioritization of alternatives, how they assessed alternatives, and an economic analysis.
Source: Toxic Use Reduction Institute

Globally Harmonized System (GHS) of Classification and Labeling of Chemicals
Abstract: Worldwide initiative to promote standard criteria for classifying chemicals according to their health, physical and environmental hazards.
Source: Environmental Protection Agency

GreenScreen(TM) (Version 1.2)
Abstract: A systematic chemical screening tool to identify substances that are inherently less hazardous. The tool uses many green chemistry principles, compiling toxicity endpoint data, and defines four benchmarks with a progressively safer chemical.
Source: Clean Production Action

Growing the Green Economy Through Green Chemistry and Design for the Environment
Abstract: This guide, developed by the Green Chemistry Commerce Council and the National Pollution Prevention Roundtable, will help state governments promote green practices, create green opportunities, and move national policy forward by providing options for promoting research, development, and use of GC and DfE to reduce hazardous chemicals in manufacturing.
Source: Washington Department of Ecology

How to Design a Safer Chemical
Abstract: Discussion of how synthetic chemists and toxicologists need to work together in designing new chemicals and molecules.

Nike Restricted Substances List and Sustainable Chemistry Guidance
Abstract: Corporate restricted substance list for every material used in Nike products, and implementation guide.
Source: Nike, Inc.

Pharmaceuticals and Personal Care Products as Pollutants (PCPP)
Abstract: Information on PPCPs, their environmental impacts, ongoing research, and environmental stewardship opportunities.
Source: Environmental Protection Agency

Pollution Prevention Options Assessment System (P2OASys)
Abstract: This systematic tool helps companies determine compare toxicity and hazard of replacement or substitution options they are considering.
Source: Toxics Use Reduction Institute (TURI)

Prevention through Design
Abstract: A protocol on preventing workplace exposures and accidents through the design of better products and processes at the earliest possible point in the life cycle.
Source: National Institute for Occupational Safety & Health

Proposition 65: Chemicals Known to Cause Cancer or Reproductive Toxicity (California) [PDF]
Abstract: The Prop65 list of toxic chemicals that are known, in the state of California, to cause cancer or reproductive harm.
Source: California Office of Environmental Health Hazard Assessment

REACH (Registration, Evaluation, Authorisation and Restriction of Chemical Substances)
Abstract: Manufacturers and importers are required to gather information on the properties of their chemical substances, which will allow their safe handling, and to register the information in a central database run by the European Chemicals Agency (ECHA).
Source: European Union

REACH Restricted Substances List (RSL)
Abstract: REACH Annex XVII places restrictions on certain hazardous substances on use in a specific product are not allowed to be used, to avoid any unnecessary testing. Typical hazardous substances that are restricted in products include lead, AZO dyes, DMF, PAHs, Phthalates, and PFOS.
Source: REACH

Risk-Screening Environmental Indicators
Abstract: RSEI is a computer-based screening tool that analyzes risk factors to put TRI release data into a chronic health context.
Source: US Environmental Protection Agency

SIN List Database
Abstract: The SIN (Substitute It Now!) List is a list of 378 chemicals that are identified as Substances of Very High Concern based on the criteria established by chemical regulation under REACH.
Source: International Chemical Secretariat

Tool for the Reduction and Assessment of Chemical and Other Environmental Impacts (TRACI)
Abstract: TRACI allows for the examination of the potential for life cycle impacts (including toxicity) associated with raw material usage and chemical releases resulting from the processes involved in producing a product.
Source: US EPA, National Risk Management Research Laboratory

Toxics Use Reduction Institute: Journal of Cleaner Production Articles, March 2011
Abstract: Annotated bibliography of articles in the March 2011 special issue of the Journal of Cleaner Production, which includes several articles discussing safer alternatives selection and implementation.
Source: Toxics Use Reduction Institute

Abstract: A wiki covering many toxic chemicals, their impacts, and current trends in toxics reduction.

U.S. EPA Design For Environment - Alternative Assessments
Abstract: This collaborative program helps industries choose safer chemicals for applications such as fire safety in circuit boards and furniture. Alternatives assessments provide a basis for informed decision making by developing an in-depth comparison of potential human health and environmental impacts.
Source: U.S. Environmental Protection Agency


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Hub Last Updated: 5/21/2015