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Biotechnology Labs: Complete List of Reference Documents
Table of Contents
Background and Overview
Operations
Reasons to Change
P2 Opportunities
Where To Go for P2 Help
Acknowledgements
Complete List of Links

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Accidents - Prevention / Air conditioning / Air monitoring / Best management practices / Biochemistry / Biological laboratories / Biological products / Biological reagents / Biotechnology / Chemical laboratories / Chemical reactions / Chemical spills / Chemical tests and reagents / Chemical tracking / Chemical treatment / More Keywords...

Browse by Resource Type
Article/report (17) / Case study/success story (2) / Fact sheet/checklist (3) / Manual/handbook/curriculum (6) / Other resources (5) / Proceedings (3) / Software/electronic tool (1) / Web site (16)

NOTE: [PDF] links require Acrobat Reader from Adobe.


- Article/report -    Top of Page

A Novel Fixative Improves Opportunities of Nucleic Acids and Proteomic Analysis in Human Archive's Tissues
Abstract: Comparison of an alternative fixative FineFIX(R), showed comparable quality performance to fresh frozen tissues. Protein extracts were compared with fresh tissues' by two-dimensional electrophoresais.
Source: Diagnostic Molecular Pathology
URL: http://www.ncbi.nlm.nih.gov/pubmed/16778593?dopt=Abstract

Amgen Finds a Way to Put Wastewater to Good Use
Abstract: News article on Amgen's water conservation efforts (Kent County, RI). Amgen has found new uses for their reverse osmosis reject water, saving 160,000 gallons of water daily.
Source: The Providence Journal
URL: http://www.projo.com/business/content/projo_20061008_amgen.1
8b568fb.html

Clearing the Air About the Latest Fume Hoods
Abstract: Learn about the latest options for more energy efficient fume hoods. Approximately 750,000 fume hoods currently in use in the U.S. - translates to approximately $3.2 billion in energy cost. (By Joanna R. Turpin)
Source: Engineered Systems
URL: http://findarticles.com/p/articles/mi_m0BPR/is_6_20/ai_10286
2286/

Decontamination, Cleanup and Associated Issues with Chemical, Biological, or Radiological Materials
Abstract: Research report discusses various decontamination and cleanup technologies, including vaporous hydrogen peroxide systems.
Source: EPA, Office of Research and Development.
URL: http://cfpub.epa.gov/si/si_public_record_report.cfm?address=
nhsrc/si/&dirEntryId=135707

Environmental Performance Metrics for Daily Use in Synthetic Chemistry [PDF]
Abstract: Describes a software tool, the Environmental Assessment Tool For Organic Syntheses (EATOS) that enables simple quantitative approach to enable chemists to compare alternative chemical syntheses on the lab bench with respect to their resource usage and the
Source: Chemistry, A European Journal
URL: http://www.metzger.chemie.uni-oldenburg.de/publikationen/pdf
/93.pdf

Gas Selection/Management for the Biotech Lab
Abstract: Ensure gas quality by certification, managing gas supply chain, and evaluating suppliers.
Source: BioPharm International (Author is Scheruing, S.)
URL: http://www.biopharminternational.com/biopharm/Supply+Chain+M
anagement+Articles/Gas-SelectionManagement-for-the-Biote
ch-Lab/ArticleStandard/Article/detail/197385

GlaxoSmithKline - Corporate Responsibility Report 2007 [PDF]
Abstract: Measures that GlaxoSmithKline is taking in pharmaceutical product design, to minimize environmental and life cycle impacts of their products and processes.
Source: GlaxoSmithKline
URL: http://www.gsk.com/content/dam/gsk/globals/documents/pdf/CR-
Report-2007.pdf

Greener Reaction Conditions Award - Codexis
Abstract: Biotech firm, Codexis, won a green chemistry award for developing an enzyme-based process to manufacture a key building block for Lipitor®. The new enzymatic processreduced waste, solvents, and the need for purification equipment.
Source: U.S. Environmental Protection Agency - Green Chemistry
URL: http://www.epa.gov/greenchemistry/pubs/pgcc/past.html#2006

Industrial and Institutional Cleaners (GS-37) [PDF]
Abstract: Environmental standards and Greenseal-approved products for institutional cleaning.
Source: Greenseal
URL: http://www.greentoclean.com/pdfs/gs37.pdf

Laboratory Waste Management Guide
Abstract: This report was prepared by the Local Hazardous Waste Management Program in King County, Washington (LHWMP.) The program seeks to reduce hazardous waste from households and small quantity generator businesses in King County by providing information and technical assistance to protect human health and the environment.
Source: Dave Waddell
URL: http://tinyurl.com/d8hsbaw

Labs21 Energy Analysis
Abstract: Applies various energy-efficient strategies to a generic laboratory under four different climate conditions. The analysis can evaluate which energy-efficient measures reap the most benefits.
Source: Labs for the 21st Century
URL: http://www.i2sl.org/resources/toolkit/casestudies.html

Pollution Prevention for Laboratories
Abstract: Checklist training handout for pollution prevention in labs - covers policies, inventory, process or equipment changes, substitution, reuse, and process efficiency.
Source: Medical Research Institute of Chemical Defense (MRICD) (histology lab)
URL: http://web.princeton.edu/sites/ehs/chemwaste/p2labs.htm

Primary Containment for Biohazards: Selection, Installation and Use of Biological Safety Cabinets
Abstract: aelection, installation and use of biological safety cabinets.
Source: U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, and National Institutes of Health
URL: http://www.cdc.gov/biosafety/

Rummaging Through the Green Chemistry Toolbox
Abstract: Synopsis of presentations for green chemistry opportunities at pharmaceuticals, including solvent selection, green design for research and drug development, and more.
Source: Green Chemistry Institute
URL: http://acsnewsservice.typepad.com/acs_news_service_weblog/20
06/06/rummaging_throu.html

Third Time Lucky
Abstract: A "third wave" of biotechnology is arriving. Will it be able to avoid a poor reception from the general public this time around? The "Economist" addresses the issue of how Biotechnology might resolve its image problem.
Source: Economist
URL: http://www.economist.com/node/13725783?story_id=13725783

US Biotech Market Analysis
Abstract: Economic trends and projections for the U.S. biotech industry. A report by RNCOS, a market research consulting Services Company specializing in BioPharma, IT & TELECOM, Retail and Services industries.
Source: RNCOS
URL: http://www.marketresearch.com/RNCOS-v3175/Biotech-6717525/

What's Going Down the Drain Can Be Money
Abstract: Offers latest technology to reduce energy and water in cage rack washing, and still achive necessary sterilization. By Beckinghausen, D.
Source: Animal Lab News
URL: http://www.alnmag.com/article/energy-efficient-washing-syste
ms


- Case study/success story -    Top of Page

Process and Environmental Technology Laboratory at Sandia [PDF]
Abstract: Describes how the design team for the new facility was able to reduce energy consumption by 40%.
Source: Laboratories for the 21st Century
URL: http://labs21.lbl.gov/docs/PETL30810.pdf

Robert S. Kerr Environmental Research Center, Energy Efficiency Upgrade
Abstract: Reduced lab energy consumption by 45% by upgrading building mechanical systems and incorporating renewable energy. Finance by an energy savings performance contract (ESPC).
Source: Labs for the 21st Century
URL: http://www.epa.gov/oaintrnt/facilities/ada.htm


- Fact sheet/checklist -    Top of Page

Biotechnology Industry Sector Permitting Guidelines for King County
Abstract: King County permitting guidelines applicable to the discharge of process wastewater from biotechnology sector facilities into sewerage facilities tributary to King County metro sewer system.
Source: King County Industrial Waste Program
URL: http://www.kingcounty.gov/environment/wastewater/IndustrialW
aste/GettingDischargeApproval/Biotech.aspx

New Biotech Tools for a Cleaner Environment
Abstract: Uses of biotech products to minimize pollution and waste in manufacturing of plastics, biofuels, and in textile finishing and pulp bleaching and production.
Source: Biotechnology Industry Association
URL: http://www.bio.org/node/3242

Pollution Prevention Opportunities at Medical Treatment Facilities
Abstract: Identifies common medical treatment facility waste streams, describes how they are generated and disposed of, and pollution prevention technologies and management practices. (by Haukdal & Strutz).
Source: U.S. Army Center for Health Promotion and Preventive Medicine
URL: http://infohouse.p2ric.org/ref/08/07295.htm


- Manual/handbook/curriculum -    Top of Page

(Manual for) Environmental Assessment Tool For Organic Syntheses (EATOS) [PDF]
Abstract: This operating manual is for software that enables chemists to compare alternative chemical syntheses for their resource usage and potential environmental impact.
Source: (By J. Metzger, and M. Eissen).
URL: http://www.metzger.chemie.uni-oldenburg.de/eatos/eatosmanual
.pdf

Chemical Fume Hood Handbook [PDF]
Abstract: Discusses hood types, function and purpose, design, performance, inspection, and safe work practices.
Source: Northwestern University
URL: http://www.research.northwestern.edu/ors/forms/chemical-fume
-hood-handbook.pdf

Energy Recovery in Laboratory Facilities [PDF]
Abstract: Provides architects, engineers, and facility managers about technologies and recommended practices in designing, constructing, and operating safe, sustainable, high-performance laboratories.
Source: Laboratories for the 21st Century, a joint program of the U.S. Environmental Protection Agency and the U.S. Department of Energy
URL: http://www1.eere.energy.gov/femp/pdfs/bp_recovery_508.pdf

Lab Waste Management Guidelines (Updated 2012) [PDF]
Abstract: These guidelines are geared for any type of lab (schools, research, clinical, biotech, analytical etc.) and some regulatory information pertains to King County, Washington, however, there are plenty of tips on waste reduction and safer alternatives.
Source: King County Local Hazardous Waste Management Program
URL: http://www.labwasteguide.org/QG_LABS_1.pdf

Lab Waste Management Guidelines (Updated 2012) [PDF]
Abstract: These guidelines are geared for any type of lab (schools, research, clinical, biotech, analytical etc.) and some regulatory information pertains to King County, Washington, however, there are plenty of tips on waste reduction and safer alternatives.
Source: King County Local Hazardous Waste Management Program
URL: http://www.labwasteguide.org/QG_LABS_1.pdf

Laboratory Ventilation
Abstract: Discusses vented equipment used in labs, biological safety cabinets, hoods and other, covering hazardous exhaust systems, high energy-efficient units, and more.
Source: American Industrial Hygiene Association (AIHA) Laboratory Health & Safety Committee
URL: http://www.aiha.org/get-involved/VolunteerGroups/LabHSCommit
tee/Pages/Technical-Topics---Laboratory-Ventilation.aspx


- Other resources -    Top of Page

Clearing Roadblocks on Critical Path
Abstract: The Critical Path Institute was formed to implement and advance findings by the FDA to accelerate and increase innovation in drug development.
Source: The Critical Path Institute
URL: http://www.dddmag.com/articles/2007/09/clearing-roadblocks-c
ritical-path

Energy Efficient Laboratory Fume Hood
Abstract: Abstract explains energy and cost benefits of low-flow fume hood over the variable air volume (VAV) hood. (Abstract only).
Source: Lawrence Berkeley National Laboratory
URL: http://www.lbl.gov/tt/techs/lbnl1205.html

Glossary of Genetic Terms
Abstract: glossary of genetic terms compiled by the Genetics Education Center.
Source: University of Kansas Medical Center
URL: http://www.kumc.edu/gec/glossnew.html

Key Green Research Areas - A Perspective from Pharmaceutical Manufacturers
Abstract: Presentation from the Green Chemisty Institute's Pharmaceutical Roundtable p on their objectives, challenges, priorities, and activities to reduce life cycle and environmental impacts
Source: Green Chemisty Institute's Pharmaceutical Roundtable
URL: http://acs.confex.com/acs/green06/techprogram/P31920.HTM

The Berkeley Hood
Abstract: Newsletter focusing on hood performance, models, and other related topics.
Source: Lawrence Berkeley National Laboratory
URL: http://ateam.lbl.gov/hightech/fumehood/Newsletter.html


- Proceedings -    Top of Page

Medical Industry Waste Prevention Round Table
Abstract: Notes from a roundtable meeting discussing numerous waste prevention tips and ideas from medical and biotech industry representatives- with a focus on solvents, alcohol and formalin.
Source: Pollution Prevention Resource Center
URL: http://www.pprc.org/mirt/meetings/medmin2.cfm

Solvent Selection Table
Abstract: Rowan University worked with Bristol-Meyers Squibb to obtain and compare chemical and environmental properties of over 50 solvents commonly used in specialty chemical and pharmaceutical industries.
Source: Rowan University
URL: http://aiche.confex.com/aiche/2006/techprogram/P67782.HTM

U.S. EPA Meeting on Pharmaceuticals in the Environment
Abstract: Summary of meeting and presentations on bioaccumulation and the environmental effects of metabolites from pharmaceuticals.
Source: US Environmental Protection Agency
URL: http://www.epa.gov/ncer/events/news/2005/08_23_05_calendar.h
tml


- Software/electronic tool -    Top of Page

Energy and Materials Flow and Cost Tracker (EMFACT)
Abstract: EMFACT is a software tool designed to be used within companies for systematically tracking materials and energy use; releases, discharges, and wastes; and associated costs in ways that can create value for their business. The tool can provide a comprehensive picture of resource use and its relation to production and planning that can help improve both business and environmental performance.
Source: Northeast Waste Management Officials' Association (NEWMOA)
URL: http://www.newmoa.org/prevention/emfact/


- Web site -    Top of Page

About Microscale Chemistry
Abstract: Describes the what, why, and how of microscale chemistry options.
Source: National Microscale Chemistry Center
URL: http://www.microscale.org/about.asp

Biotechnology Industry Facts
Abstract: Background and market statistics on the biotech industry.
Source: Biotechnology Industry Organization
URL: http://www.bio.org/node/517

Clean Cities
Abstract: Clean Cities is part of the Office of Energy Efficiency and Renewable Energy's Vehicle Technologies Program. Its goal is to advance the nation's economic, environmental, and energy security by supporting local decisions to adopt practices that contribute to the reduction of petroleum consumption.
Source: US Department of Energy
URL: http://www1.eere.energy.gov/cleancities/

Defining Pollution Prevention
Abstract: Pollution prevention (P2) is defined to mean: source reduction and other practices that reduce or eliminate the creation of pollutants through increased efficiency in the use of raw materials, energy, water, or other resources, or protecting resources through conservation.
Source: Washington Department of Ecology
URL: http://www.ecy.wa.gov/programs/hwtr/P2/whatisp2.html

Frequently asked Questions (FAQ) for Reagent Recycling
Abstract: FAQs regarding filter and gravitational recycling systems for alcohol, xylene, and formalin.
Source: Creative Waste Solutions
URL: http://www.cwsincorp.com/faq.htm

Green Chemistry Institute Pharmaceutical Roundtable
Abstract: [Requires registration] The Green Chemistry Institute (GCI) and global pharmaceutical corporations developed the roundtable to encourage innovation while catalyzing the integration of green chemistry and green engineering in the pharmaceutical industry.
Source: American Chemical Society
URL: http://portal.acs.org/portal/acs/corg/content?_nfpb=true&_pa
geLabel=PP_TRANSITIONMAIN&node_id=830&use_sec=false&sec_
url_var=region1

Green Chemistry Institute Pharmaceutical Roundtable
Abstract: [Requires registration] The Green Chemistry Institute (GCI) and global pharmaceutical corporations developed the roundtable to encourage innovation while catalyzing the integration of green chemistry and green engineering in the pharmaceutical industry.
Source: American Chemical Society
URL: http://portal.acs.org/portal/acs/corg/content?_nfpb=true&_pa
geLabel=PP_TRANSITIONMAIN&node_id=830&use_sec=false&sec_
url_var=region1

Green Engineering Website
Abstract: Green engineering website for educators and students.
Source: American Society for Engineering Education
URL: http://nebula.rowan.edu:82/home.asp

Packaging
Abstract: Resources to help users of packaging save money through changes that reduce packaging waste and the environmental burdens of packaging
Source: Oregon Department of Environmental Quality
URL: http://www.deq.state.or.us/lq/sw/packaging/

Pollution Prevention Ideas for Labs
Abstract: reducing or eliminating chemical use and chemical Suggestions for research, academic, and analysis labs to reduce waste production; substitute less hazardous materials; conserve water or electricity; and other means of reducing environmental impact.
Source: Princeton University
URL: http://web.princeton.edu/sites/ehs/chemwaste/p2labs.htm

Sewer Disposable Liquid Scintillation Cocktails
Abstract: There are only three LSC products currently approved by the State of Washington Department of Ecology for disposal down the sanitary sewer. They are soluble (or readily dispersible) in water and contain less than 10% non-ionic surfactants.
Source: University of Washington
URL: http://www.ehs.washington.edu/rsowaste/rad_scint_sewer.shtm

ThermoSafe Insulated Shipping Thermal Packaging Solutions
Abstract: ThermoSafe Brands is the leader in temperature assurance solutions for the pharmaceutical, biotech, medical, food service, food processing and gift food industries.
Source: ThermoSafe
URL: http://www.thermosafe.com/index.html?Pr10=Science

TRI Chemicals
Abstract: The current TRI toxic chemical list contains 581 individually listed chemicals and 30 chemical categories (including 3 delimited categories.
Source: EPA
URL: http://www2.epa.gov/toxics-release-inventory-tri-program

University of Delaware Shared Core Instrumentation Centers in the Life Sciences
Abstract: Description of capabilities and typical operations for biotech research.
Source: Delaware biotechnology Institute
URL: http://www.dbi.udel.edu/core/sharedfac.html

University of Delaware Shared Core Instrumentation Centers in the Life Sciences
Abstract: Description of capabilities and typical operations for biotech research.
Source: Delaware biotechnology Institute
URL: http://www.dbi.udel.edu/core/sharedfac.html

Western Blotting Workflow
Abstract: Highlights new tools for protein blotting.
Source: Invitrogen
URL: http://www.invitrogen.com/site/us/en/home/Products-and-Servi
ces/Applications/Protein-Expression-and-Analysis/Western
-Blotting/WBlot-misc/Western-Blotting-Workflow.html

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Hub Last Updated: 1/16/2014